Rapid diagnostic point of care tests in resource limited settings

An Assessment of the Technological Issues and Options for Point-Of-Care Diagnostic Tests in Resource-Limited Settings

Feasibility of HIV point-of-care tests for resource-limited settings: challenges and solutions

Improved access to anti-retroviral therapy increases the need for affordable monitoring using assays such as CD4 and/or viral load in resource-limited settings. Barriers to accessing treatment, high rates of loss to initiation and poor retention in care are prompting the need to find alternatives to conventional centralized laboratory testing in certain countries. Strong advocacy has led to a r...

Utility of Point-of-Care Malaria Rapid Diagnostic Tests

In their short report on the utility of a point-of-care malaria rapid diagnostic test (RDT) in HIV-infected adults, Mills and others conclude that “the rapid diagnostic test accurately ruled “in or out” malaria.” 1 However, at a positive predictive value of 70.6% and a lower confidence limit of 44.0%, it is difficult to state that the test accurately rules in malaria. At the “rule out” side, th...

HIV Care & PMTCT in Resource-Limited Settings

edited. Objectives: We aimed to compare the incidence of meningococcal disease amongst HIV-infected and uninfected individuals and to evaluate whether HIV is a risk factor for mortality and bacteremia amongst patients with meningococcal disease. Design: Cohort surveillance study. Methods: We conducted laboratory-based surveillance for meningococcal disease in Gauteng Province, South Africa. HIV...

Maximizing the Delivery Performance of Point-of-Care CD4+ T-Cell Counting Tests in Resource-Limited Settings - A Policy Brief

Managing HIV/AIDS presents challenges to public health policymakers, frontline workers, and researchers worldwide. A key strategy in the disease management is early diagnosis and rapid treatment initiation. While the technological field of point‐of‐care HIV/AIDS diagnostics has advanced significantly in the past two decades, several critical issues remain that hinder the deployment of point‐of‐...